On shock absorbent insoles to prevent bone fractures.

Bone mineral density thresholds for pharmacological intervention to prevent fractures.

BACKGROUND Treatment intervention thresholds for prevention of osteoporotic fractures can be derived from reports from the World Health Organization (diagnostic criteria) and National Osteoporosis Foundation (treatment criteria). It is not known how well these thresholds work to identify women who will fracture and are therefore candidates for treatment interventions. We used data from the Nati...

are physicians ready to prevent osteoporotic fractures in hemodialysis patients?

Alendronate treatment to prevent osteoporotic fractures.

Alendronate sodium, an aminobisphosphonate, has been approved by the Food and Drug Administration for the prevention and treatment of osteoporosis in postmenopausal women, thus providing an effective alternative to estrogen replacement therapy in women who cannot or will not take estrogen. Large, randomized, controlled trials have demonstrated approximately a 50% reduction in vertebral, hip, an...

Long term comparison of some shock attenuating insoles.

The effect of one years general use on the performance of four shock attenuating insoles is reported. Testing was carried out using the JP Biomechanics Shock Meter on twelve volunteers on a timed oval course at eight intervals during the year. The results show that two of the insoles perform well (Viscolas and PPT) although deterioration does occur after 6-9 months use; the other two insoles (P...

On soups, hips and humeri (Frank Rauch) Strong muscles prevent bone loss, fractures and death

How to study musculoskeletal interactions in clinical studies? A popular method is what might be called the ‘multiple regression soup’ approach. Mix a number of cross-sectional bone and muscle data, add a generous amount of confounders and stir for a while, until P values below 0.05 pop up. Such studies tend to generate conclusions like: ‘Although pinch strength is a strong determinant of femor...